Grizzlies-Sixers NBA expert prediction and odds for Wednesday, March 6 (Back Memphis as an underdog)

NBA betting preview, prediction and best bet for Grizzlies-Sixers.
Feb 26, 2024; Memphis, Tennessee, USA; Memphis Grizzlies guard Luke Kennard (10) shoots for three.
Feb 26, 2024; Memphis, Tennessee, USA; Memphis Grizzlies guard Luke Kennard (10) shoots for three. / Petre Thomas-USA TODAY Sports

Philadelphia had a brief two-game winning streak snapped in a 112-107 road loss to Brooklyn Tuesday night. The 76ers have a quick turnaround in their return home Wednesday when the Grizzlies come to town. Philadelphia has fallen to the No. 7 seed after being leapfrogged by the Miami Heat.

Can they get back on track and in the playoff mix Wednesday night against the lowly Grizzlies? 

Memphis, derailed by a plethora of injuries this season, snapped a five-game losing streak with a defensive-minded 106-102 win over the Nets on the road Monday.

Can they cover again as underdogs Wednesday night in Philadelphia? Here’s the betting breakdown of the matchup with a best bet. 

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Grizzlies vs. Sixers odds, spread and total

Grizzlies vs. Sixers how to watch

  • Date: Wednesday, March 6
  • Game time: 7:30 p.m. EST
  • Venue: Wells Fargo Center
  • How to watch (TV): Bally Sports
  • Grizzlies record: 21-41
  • Sixers record: 35-26


Grizzlies vs. Sixers injury report

Memphis Grizzlies

  • Yutu Watanabe (wrist): out
  • Jaren Jackson Jr. (quad): questionable

Philadelphia 76ers

  • Tyrese Maxey (concussion): questionable 

Grizzlies vs. Sixers key players to watch


Luke Kennard: The former first-round pick missed two games but returned on Saturday with 5 points and 5 assists in an overtime loss to Portland. In Monday’s win over Brooklyn, though, Kennard had 25 points on 8-of-11 shooting, knocking down six triples. Kennard has now scored in double figures in six of his last eight outings. 


Kelly Oubre Jr.: Playing without Tyrese Maxey (concussion), Oubre poured in a season-high 30 points on 11-of-20 shooting to go with six rebounds and four assists in Tuesday’s loss at Barclays Center. Oubre has scored 51 points over the last two games combined, going 18-of-37 from the field and 15-of-25 from inside the arc. 

Grizzlies vs. Sixers prediction and pick

The Grizzlies have been bitten hard by the injury bug this season and that has continued with Jaren Jackson Jr. (22.4 points per game) missing the last three games.

However, the Sixers are going through bad injury luck, as well, and could be without Maxey for the second straight night in addition to having reigning MVP Joel Embiid sidelined by a knee injury for over a month. 

NBA unders have been on fire since the All-Star break, and the path to another low-scoring rockfight is there for this matchup with two top-tier scorers trending toward not suiting up. However, the points seem more valuable on the Memphis side given the Grizzlies’ above-average defense (No. 10 in net rating) facing a Philadelphia offense that will likely need to rely on guys like Tobias Harris and Buddy Hield to carry the load. 

Despite a tough season, Memphis has been hanging tough with opponents this season, covering in seven of its last nine games as an underdog. Meanwhile, you’re asking a Philadelphia offense missing its top-2 scorers to win by margin. The 76ers are just 1-5 ATS as a favorite since Embiid went down. Take the points with the Grizzlies. 

Game odds update periodically and are subject to change.