Grizzlies vs. Cavaliers NBA expert prediction and odds for Wednesday, April 10 (Memphis thrives on road)

Betting odds, pick and prediction for the Memphis Grizzlies-Cleveland Cavaliers matchup in the NBA on Wednesday.
Memphis Grizzlies forward GG Jackson.
Memphis Grizzlies forward GG Jackson. / Petre Thomas-USA TODAY Sports

The Memphis Grizzlies are playing the second night of a back-to-back in a huge game for the Cleveland Cavaliers on Wednesday.

Cleveland is just 3-7 in its last 10 games, and it fell in the standings after blowing a 26-point lead against the Los Angeles Clippers on Sunday.

The Cavs would love to finish in a top-three seed in the East, but they’ll need to close out this season very strong with the New York Knicks, Orlando Magic, and Milwaukee Bucks all battling for a top spot in the conference. 

Memphis is out of things in the West, but the team has been frisky on the road all season long, going 18-22 straight up. Can they pick up a road win on the second night of a back-to-back? 

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Here’s a look at the latest odds and my best bet for this game: 

Grizzlies vs. Cavaliers odds, spread and total

Grizzlies vs. Cavaliers how to watch

  • Date: Wednesday, April 10
  • Time: 7:00 p.m. EST
  • Venue: Rocket Mortgage Fieldhouse
  • How to watch (TV): Bally Sports Southeast, Bally Sports Ohio
  • Grizzlies record: 27-52
  • Cavs record: 46-33

Grizzlies vs. Cavaliers injury reports

Grizzlies injury report

  • Not submitted yet

Cavs injury report

  • Ty Jerome – out
  • Donovan Mitchell – available
  • Sam Merrill – doubtful
  • Dean Wade – out

Grizzlies vs. Cavaliers key players to watch

Memphis Grizzlies

GG Jackson II: Memphis’ rookie forward scored in double figures in 14 straight games ahead of Tuesday’s matchup against the San Antonio Spurs. Over that stretch, Jackson is averaging 18.5 points, 5.1 rebounds, and 2.2 assists per game while shooting 44.6 percent from the field. He finished Tuesday’s game with 11 points on just 4-of-17 shooting from the field. 

Cleveland Cavaliers

Darius Garland: Darius Garland has scored 26 and 28 points in his last two games, a positive sign for the Cavs. The team needs him to turn things around ahead of the playoffs after he averaged just 17.9 points per game on 42.6 percent from the field in March. 

Grizzlies vs. Cavaliers prediction and pick

I do not trust the Cavs to cover this massive number on Wednesday, even with Memphis potentially sitting players on the second night of a back-to-back.

The Cavs have gone just 13-15-1 against the spread as home favorites this season, and they have played some of their worst basketball of the season in their last 10 games.

Over that stretch, Cleveland ranks 24th in the NBA in net rating and 27th in defensive rating. Not good for a team looking to compete for a title. 

Meanwhile, the Grizzlies are 20-15 against the spread as road underdogs, and they’ve been able to win outright in nearly half of their road games. Yes, the team lost badly to San Antonio last night, but that game was in Memphis.

Asking Cleveland to cover almost 20 points just one game after it blew a 26-point lead is too rich for my blood.

I’ll take Memphis to hang around – if you can call it that – in this one. 

Pick: Grizzlies +18.5 (-110)

Game odds refresh periodically and are subject to change.

Find Peter Dewey's NBA betting record here (futures included). You can also follow my daily plays on BetStamp here.