Grizzlies vs. Pistons prediction and odds for Wednesday, Dec. 6 (Take Memphis on the road)

A full betting preview of Wednesday night's matchup between the Memphis Grizzlies and the Detroit Pistons.
Nov 29, 2023; Memphis, Tennessee, USA; Memphis Grizzlies forward-center Jaren Jackson Jr. (13)
Nov 29, 2023; Memphis, Tennessee, USA; Memphis Grizzlies forward-center Jaren Jackson Jr. (13) / Petre Thomas-USA TODAY Sports

The Memphis Grizzlies will travel to the Motor City to play the Detroit Pistons on Wednesday night. The Grizzlies are coming off a tough loss against the Suns, but will hopefully rebound against Detroit, which has lost 17 straight games.

Memphis opened as a 1.5-point road favorite over Detroit, but that number has moved to 2.5. The Pistons have struggled mightily in Monty Williams' first year as head coach as they looked poised to be back in the lottery again. 

Here are the odds and our best bet for Memphis-Detroit:

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Grizzlies vs. Pistons odds, spread and total

Grizzlies vs. Pistons how to watch

  • Date: Wednesday, Dec. 6
  • Game Time: 7:00 p.m. EST
  • Venue: Little Caesars Arena
  • How to Watch (TV): Bally Sports DET, Bally Sports SE-MEM
  • Grizzlies Record: 5-14
  • Pistons Record: 2-18

Grizzlies vs. Pistons injury reports

Memphis Grizzlies injury report

  • Luke Kennard – out

Detroit Pistons injury report

  • Joe Harris – doubtful
  • Marvin Bagley III – probable

Grizzlies vs. Pistons key players to watch

Memphis Grizzlies

Jaren Jackson Jr.: The 24-year-old forward is coming off his best game of the season against the Suns last weekend. Jackson Jr. led the Grizzlies with 37 points (13-for-21 FG, 2-for-5 from 3) and had nine rebounds. With Morant still suspended, Memphis has had to lean on Desmond Bane and Jackson to carry the offensive workload. The young big man will try to build off this performance against the Pistons, who have lost 17 consecutive games.

Detroit Pistons

Cade Cunningham: Cunningham has been one of the lone bright spots on the Pistons amid their 17-game losing streak. The former No. 1 overall pick is averaging 22.4 points, 7.3 assists, and 3.9 rebounds per game this season. Cunningham will look to lead the Pistons to their first win since October, but it won’t be easy, as the Grizzlies have won two out of their last three road games.

Grizzlies vs. Pistons prediction and pick

If you think this is the spot where the Pistons will snap their losing streak, think again. The Grizzlies have played well on the road this season (4-6) and just defeated the Dallas Mavericks sans Luka Doncic by 14 points.

Even though the Grizzlies are without Morant and a host of other players due to injury, they still have one of the better defenses in the league this season. Memphis is ranked 11th in opponent points per game (111.9) and 10th in DRtg (112.2). They leave a lot to be desired offensively, but this Pistons’ squad also struggles to score points (109.2 ppg/27th in the NBA) and can’t defend (118.1 ppg allowed/23rd in the NBA).

Based on those stats, I expect at least 50 points scored between Jackson Jr. and Bane against Detroit. The Grizzlies are 3-4 against the spread as a favorite this season, while the Pistons are 3-4-1 ATS as home underdogs. Cunningham will do what he can for Detroit, but I don’t trust them to hold up defensively for all four quarters.

Game odds refresh periodically and are subject to change.